By combining large-scale experiments with deep learning, researchers built a lightweight model that deciphers how regulatory DNA controls gene activity.
Gene regulation is far more predictable than previously believed, scientists conclude after developing the deep learning ...
Deep-learning model decodes the regulatory effects of DNA changes ...
Fixing gene defects with designer DNA is on the horizon after Google DeepMind launched a pioneering new AI tool.
IPA, a non-coding RNA from the CUL1 gene that stabilizes the nucleolus and supports ribosome production. Removing it ...
(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...
It could transform our understanding of why diseases develop and the medicines needed to treat them, says researchers.
There are some genes that can promote cancer; they are sometimes called oncogenes, and in tumor cells, mutations are often found in these genes. When they are functioning normally, oncogenes are often ...
Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...
Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...