Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — ...

近期，International Journal of Biological Macromolecules期刊在线发表了题为“IAV inhibits the host antiviral defense mediated by LncRNA-LRIR to enhance viral replication”的研究成果（PMID: 40780338）。该研究揭示了甲型流感病毒（Influenza ...

Long non-coding RNAs exist in the so-called "Wild West" (99%) of the human genome that is currently understudied. Not only does this finding have treatment implications for patients with ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

Impact of variant allele frequency (VAF) of TP53 alterations and Signatera circulating tumor DNA (ctDNA) monitoring for patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab ...

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

Scientists profiling small non-coding RNAs in postmortem brain tissue from people with schizophrenia and bipolar disorder have identified sweeping molecular disruptions that extend well beyond the ...

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with night blindness in youth and progresses to tunnel vision as ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

RNA，作为细胞信号传导的重要使者，在许多疾病中扮演着重要的角色，无论是神经退行性疾病还是衰老，都有研究者在开发相应的RNA疗法。 西湖大学讲席教授付向东自1992年建实验室时起，就一直在做RNA方面的基础研究和转化应用。他于2010年入选美国科学促进会 ...