The advent of single-cell omics technologies has revolutionized our understanding of the complex cellular landscape in cancer. Traditional bulk sequencing ...
Researchers at VIB and VUB have developed a powerful new way to study how the immune system behaves inside lung tumors. By combining a patient-relevant mouse model with single-cell technologies, the ...
中国单细胞与空间组学系列论坛近日,东南大学附属中大医院研究团队在期刊《Journal for ImmunoTherapy of Cancer》上发表了研究论文,题为“Single-cell and spatial transcriptomics reveal that the CXCL12–CXCR4 axis drives the immune-desert phenotype in small ...
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Advancing single-cell transcriptomics into the mainstream of biomedical research
Kelly Parliament, staff application scientist at Beckman Coulter Life Sciences, discusses how automation is improving the efficiency of single-cell transcriptomic workflows.
Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...
VIB-VUB researchers have developed a patient-relevant lung adenocarcinoma model combined with SEPARATE-Seq technology to ...
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Inside tumors, immune cells hide a split personality—and one side could quietly decide cancer's fate
Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely ...
Researchers demonstrate improved spatial mapping technology that enhances transcript detection, identifies key tumor cell ...
Glioblastoma (GBM) is an aggressive type of brain cancer that is known to be very difficult to treat. One reason why this ...
Immune checkpoint blockade (ICB) has reshaped modern immunotherapy by unleashing antitumor immune responses through targeting inhibitory immune checkpoints ...
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