Abstract: Multiple Sequence Alignment (MSA) is a fundamental NP-hard problem in Bioinformatics, central to numerous sequence analysis tasks. Despite extensive research, existing approaches still ...

1 Department of Science and High Technology, University of Insubria, Como, Italy 2 Center of Neuroscience Research, University of Insubria, Busto Arsizio, Italy Introduction: i-Motifs (iMs) are ...

WitChi is an analysis and pruning tool designed to evaluate and reduce compositional bias in multiple sequence alignments (MSAs). It utilizes statistical methods, permutation tests, and parallel ...

Our STOCKHOLM File Format Converter is a specialized bioinformatics utility designed to improve interoperability among multiple sequence alignments (MSAs). This tool expertly converts alignments from ...

salti is a standalone, self-contained terminal user interface (TUI) application designed for the browsing and inspection of multiple sequence alignments in FASTA format. The application operates ...

ABSTRACT: Genomic surveillance has proven to be a critical source of information for understanding and responding to the COVID-19 pandemic. In Africa, genomic surveillance was very limited, and few ...

ABSTRACT: Genomic surveillance has proven to be a critical source of information for understanding and responding to the COVID-19 pandemic. In Africa, genomic surveillance was very limited, and few ...

Aligning large language models (LLMs) with human values remains difficult due to unclear goals, weak training signals, and the complexity of human intent. Direct Alignment Algorithms (DAAs) offer a ...